Verdict: if you are choosing Python for agentic AI work in 2026 and you want one answer, pick LangGraph . Its explicit graph-and-state model gives you deterministic routing, durable checkpoints you can inspect, and the largest surrounding ecosystem, which is what actually matters once an agent runs unattended. Microsoft Agent Framework (MAF) is the better pick if your infrastructure already lives in Azure, because it is the direct successor to AutoGen and Semantic Kernel and carries the en...